microneedling with pdrn

Microneedling with PDRN is a skin rejuvenation treatment that combines tiny micro-injuries from microneedling with PDRN (Polydeoxyribonucleotide), a DNA fragment derived from salmon reproductive cells. This helps stimulate collagen production, repair tissue, and deeply hydrate the skin.

PDRN promotes tissue repair at a cellular level by stimulating DNA synthesis, enhancing collagen production, improving elasticity, and accelerating healing. It also provides hydration and revitalization for a radiant, youthful complexion.

• Fine lines and wrinkles

• Acne scars and other textural irregularities

• Sun damage and hyperpigmentation

• Loss of elasticity and sagging skin

• Dull or dehydrated skin

The total treatment time is 1 hour and 45 minutes which includes:

• 15 minutes for the numbing cream application

• 30 minutes for the numbing cream to set

• 1 hour for the microneedling itself.

Almost anyone looking to improve skin texture, firmness, and hydration is a candidate. People with active infections, severe acne, or certain medical conditions may need to consult with a provider first.

Most patients experience minimal discomfort. A topical numbing cream is applied before treatment to ensure maximum comfort.

Downtime is minimal. You may experience mild redness, slight swelling, or tiny pinpoint marks for 24–48 hours, but most patients return to daily activities immediately.

Some hydration and brightness may be noticeable immediately, but collagen stimulation and skin repair take 4–6 weeks to show full results.

Unlike PRP/PRF, which uses the patient’s blood to stimulate growth factors, PDRN directly supports DNA repair, hydration, and tissue regeneration. It is less variable than PRP and provides a strong anti-aging and skin-repair effect.

Side effects are rare but may include temporary redness, mild swelling, or irritation. PDRN is low immunogenic, making allergic reactions uncommon.

• Avoid direct sun exposure for 24–48 hours

• Use gentle cleansers and moisturizers (we provide an after-care kit with our line of medical grade skincare products

• Avoid retinoids and acids for a few days

PDRN is derived from salmon DNA fragments. While the extraction process significantly reduces allergenic proteins, there is a potential risk for individuals with severe fish allergies. If you have a known fish allergy, it’s important to:

• Inform your provider before treatment

• Undergo an allergy assessment if needed

• Consider alternative treatments if your allergy is severe